Pooja and Joanne teamed up to write an extensive review of mitochondrial and metabolic dysfunction in neurodegenerative disease development and progression, “Reappraisal of metabolic dysfunction in neurodegeneration: Focus on mitochondrial function and calcium signaling” published in the July issue of Acta Neuropathologica Communications (https://doi.org/10.1186/s40478-021-01224-4).